[HTML][HTML] A review of granulocyte colony-stimulating factor receptor signaling and regulation with implications for cancer
SD Park, AS Saunders, MA Reidy, DE Bender… - Frontiers in …, 2022 - frontiersin.org
… its receptor granulocyte colony-stimulating factor receptor (… which isoforms are expressed
in non-hematopoietic cells, … ) and class IV (differentiation defective) GCSFR isoforms are …
in non-hematopoietic cells, … ) and class IV (differentiation defective) GCSFR isoforms are …
G-CSF, the guardian of granulopoiesis
HM Mehta, SJ Corey - Seminars in Immunology, 2021 - Elsevier
… growth in comparison to the Class I isoform. The Class III … Another pathway that inhibits
internalized CSF3R involves the ER-… IV granulocyte colony-stimulating factor receptor isoform …
internalized CSF3R involves the ER-… IV granulocyte colony-stimulating factor receptor isoform …
Alternatively spliced CSF3R isoforms in SRSF2 P95H mutated myeloid neoplasms
BA Wang, HM Mehta, SR Penumutchu, BS Tolbert… - Leukemia, 2022 - nature.com
… encodes the granulocyte colony stimulating factor receptor (G… SRSF2 P95 mutations have
been shown to preferentially bind to … had demonstrated selective growth of monosomy 7 cells …
been shown to preferentially bind to … had demonstrated selective growth of monosomy 7 cells …
Disappearance of monosomy 7 in a patient with aplastic anemia after eltrombopag treatment
Y Uchibori, A Hangaishi, Y Kamoda, M Hirao… - …, 2020 - Taylor & Francis
… link between thrombopoietin receptor signaling and cytogenetic … cyclosporine with
granulocyte-colony-stimulating factor (G-… dL, and a platelet count of 2.8×10 4 /μL before treatment …
granulocyte-colony-stimulating factor (G-… dL, and a platelet count of 2.8×10 4 /μL before treatment …
Cytokine receptor splice variants in hematologic diseases
B Wang, H Mehta - Cytokine, 2020 - Elsevier
… are granulocyte colony stimulating factor 3 (CSF3/GCSF), … Class IV were also observed
in patient cells with monosomy 7, … were seen to be preferentially associated with alternative …
in patient cells with monosomy 7, … were seen to be preferentially associated with alternative …
Alternatively Spliced CSF3R in Human Health and Disease
BA Wang - 2022 - scholarscompass.vcu.edu
… Elevated alternative colony stimulating factor 3 receptor (CSF3R) isoforms, called classes, …
to preferentially stimulate the proliferation of monosomy 7 cells bearing the Class IV isoform …
to preferentially stimulate the proliferation of monosomy 7 cells bearing the Class IV isoform …
Altered expression of CSF3R splice variants impacts signal response and is associated with SRSF2 mutations
A Lance, LJ Druhan, CG Vestal, NM Steuerwald… - Leukemia, 2020 - nature.com
… the receptor for granulocyte-colony stimulating factor (G-CSF), … overall G-CSF stimulated
proliferation is determined by the … the granulocyte colony-stimulating factor receptor orchestrate …
proliferation is determined by the … the granulocyte colony-stimulating factor receptor orchestrate …
Treatment optimization and genomic outcomes in refractory severe aplastic anemia treated with eltrombopag
… growth factors, especially granulocyte colony-stimulating … the monosomy 7 clone, suggesting
the transformed monosomy … may be preferentially stimulated by EPAG to proliferate. One …
the transformed monosomy … may be preferentially stimulated by EPAG to proliferate. One …
Analyzing the relation between cytokine IL-2 and cytogenetic abnormalities in acquired aplastic anemia patients
A Dutta, R De, TK Dolai, A Halder - Contemporary Medical Biotechnology …, 2022 - Elsevier
… The tubes were kept at 4C overnight. The next … receptor isoform delivers a faulty signal of
proliferation, nonetheless differentiation [10]. The incidence of a minor number of monosomy 7 …
proliferation, nonetheless differentiation [10]. The incidence of a minor number of monosomy 7 …
Molecular genetics of myeloid malignancy predisposition: Insights into pathogenesis and therapeutic translation
M Krutein - 2019 - digital.lib.washington.edu
… Granulocyte colony-stimulating factor preferentially stimulates proliferation of monosomy
7 cells bearing the isoform IV receptor. Proc Natl Acad Sci US A. 2006;103(39):14483-8. …
7 cells bearing the isoform IV receptor. Proc Natl Acad Sci US A. 2006;103(39):14483-8. …